WEB-based GEne SeT AnaLysis Toolkit
 
Translating gene lists into biological insights...
 


User data and parameters: User data: textAreaUpload.txt, Organism: hsapiens, Id Type: ensembl_gene_stable_id, Ref Set: entrezgene, Significance Level: Top10, Statistics Test: Hypergeometric, MTC: BH, Minimum: 2

The results for the enriched GO category are listed in this table. For each GO category, the first row lists its sub-root (biological process, molecular function, or cellular component), category name, and corresponding GO ID.
The second row lists the following statistics:
Finally, genes in the category are listed. For each gene, the table lists the user uploaded ID and value (optional), Entrez ID, Ensembl Gene Stable ID, Gene symbol, and description. Ensembl Gene Stable ID and Entrez Gene ID are linked to the Ensembl and Entrez Gene databases, respectively.

Database:biological process       Name:immune response       ID:GO:0006955
C=1071; O=66; E=8.49; R=7.77; rawP=1.04e-44; adjP=1.08e-41
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000107201 NA DDX58 DEAD (Asp-Glu-Ala-Asp) box polypeptide 58 23586 ENSG00000107201
2  ENSG00000204287 NA HLA-DRA major histocompatibility complex, class II, DR alpha 3122 ENSG00000204287
3  ENSG00000204592 NA HLA-E major histocompatibility complex, class I, E 3133 ENSG00000204592
4  ENSG00000204642 NA HLA-F major histocompatibility complex, class I, F 3134 ENSG00000204642
5  ENSG00000006210 NA CX3CL1 chemokine (C-X3-C motif) ligand 1 6376 ENSG00000006210
6  ENSG00000168394 NA TAP1 transporter 1, ATP-binding cassette, sub-family B (MDR/TAP) 6890 ENSG00000168394
7  ENSG00000068079 NA IFI35 interferon-induced protein 35 3430 ENSG00000068079
8  ENSG00000089041 NA P2RX7 purinergic receptor P2X, ligand-gated ion channel, 7 5027 ENSG00000089041
9  ENSG00000166710 NA B2M beta-2-microglobulin 567 ENSG00000166710
10  ENSG00000132274 NA TRIM22 tripartite motif containing 22 10346 ENSG00000132274
11  ENSG00000089127 NA OAS1 2'-5'-oligoadenylate synthetase 1, 40/46kDa 4938 ENSG00000089127
12  ENSG00000223865 NA HLA-DPB1 major histocompatibility complex, class II, DP beta 1 3115 ENSG00000223865
13  ENSG00000183486 NA MX2 myxovirus (influenza virus) resistance 2 (mouse) 4600 ENSG00000183486
14  ENSG00000185885 NA IFITM1 interferon induced transmembrane protein 1 8519 ENSG00000185885
15  ENSG00000137959 NA IFI44L interferon-induced protein 44-like 10964 ENSG00000137959
16  ENSG00000196126 NA HLA-DRB1 major histocompatibility complex, class II, DR beta 1 3123 ENSG00000196126
17  ENSG00000138755 NA CXCL9 chemokine (C-X-C motif) ligand 9 4283 ENSG00000138755
18  ENSG00000131203 NA IDO1 indoleamine 2,3-dioxygenase 1 3620 ENSG00000131203
19  ENSG00000231389 NA HLA-DPA1 major histocompatibility complex, class II, DP alpha 1 3113 ENSG00000231389
20  ENSG00000111335 NA OAS2 2'-5'-oligoadenylate synthetase 2, 69/71kDa 4939 ENSG00000111335
21  ENSG00000197646 NA PDCD1LG2 programmed cell death 1 ligand 2 80380 ENSG00000197646
22  ENSG00000156587 NA UBE2L6 ubiquitin-conjugating enzyme E2L 6 9246 ENSG00000156587
23  ENSG00000108771 NA DHX58 DEXH (Asp-Glu-X-His) box polypeptide 58 79132 ENSG00000108771
24  ENSG00000204264 NA PSMB8 proteasome (prosome, macropain) subunit, beta type, 8 (large multifunctional peptidase 7) 5696 ENSG00000204264
25  ENSG00000164342 NA TLR3 toll-like receptor 3 7098 ENSG00000164342
26  ENSG00000213928 NA IRF9 interferon regulatory factor 9 10379 ENSG00000213928
27  ENSG00000162645 NA GBP2 guanylate binding protein 2, interferon-inducible 2634 ENSG00000162645
28  ENSG00000204267 NA TAP2 transporter 2, ATP-binding cassette, sub-family B (MDR/TAP) 6891 ENSG00000204267 ENSG00000250264
29  ENSG00000160710 NA ADAR adenosine deaminase, RNA-specific 103 ENSG00000160710
30  ENSG00000111331 NA OAS3 2'-5'-oligoadenylate synthetase 3, 100kDa 4940 ENSG00000111331
31  ENSG00000137752 NA CASP1 caspase 1, apoptosis-related cysteine peptidase 834 ENSG00000137752
32  ENSG00000239713 NA APOBEC3G apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3G 60489 ENSG00000239713
33  ENSG00000100342 NA APOL1 apolipoprotein L, 1 8542 ENSG00000100342
34  ENSG00000138496 NA PARP9 poly (ADP-ribose) polymerase family, member 9 83666 ENSG00000138496
35  ENSG00000157601 NA MX1 myxovirus (influenza virus) resistance 1, interferon-inducible protein p78 (mouse) 4599 ENSG00000157601
36  ENSG00000100448 NA CTSG cathepsin G 1511 ENSG00000100448
37  ENSG00000198574 NA SH2D1B SH2 domain containing 1B 117157 ENSG00000198574
38  ENSG00000196735 NA HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1 3117 ENSG00000196735
39  ENSG00000184979 NA USP18 ubiquitin specific peptidase 18 11274 ENSG00000184979
40  ENSG00000242574 NA HLA-DMB major histocompatibility complex, class II, DM beta 3109 ENSG00000242574
41  ENSG00000121858 NA TNFSF10 tumor necrosis factor (ligand) superfamily, member 10 8743 ENSG00000121858
42  ENSG00000119917 NA IFIT3 interferon-induced protein with tetratricopeptide repeats 3 3437 ENSG00000119917
43  ENSG00000135114 NA OASL 2'-5'-oligoadenylate synthetase-like 8638 ENSG00000135114
44  ENSG00000019582 NA CD74 CD74 molecule, major histocompatibility complex, class II invariant chain 972 ENSG00000019582
45  ENSG00000187608 NA ISG15 ISG15 ubiquitin-like modifier 9636 ENSG00000187608
46  ENSG00000179583 NA CIITA class II, major histocompatibility complex, transactivator 4261 ENSG00000179583
47  ENSG00000132530 NA XAF1 XIAP associated factor 1 54739 ENSG00000132530
48  ENSG00000170581 NA STAT2 signal transducer and activator of transcription 2, 113kDa 6773 ENSG00000170581
49  ENSG00000204257 NA HLA-DMA major histocompatibility complex, class II, DM alpha 3108 ENSG00000204257
50  ENSG00000205220 NA PSMB10 proteasome (prosome, macropain) subunit, beta type, 10 5699 ENSG00000205220
51  ENSG00000119922 NA IFIT2 interferon-induced protein with tetratricopeptide repeats 2 3433 ENSG00000119922
52  ENSG00000169245 NA CXCL10 chemokine (C-X-C motif) ligand 10 3627 ENSG00000169245
53  ENSG00000169248 NA CXCL11 chemokine (C-X-C motif) ligand 11 6373 ENSG00000169248
54  ENSG00000134321 NA RSAD2 radical S-adenosyl methionine domain containing 2 91543 ENSG00000134321
55  ENSG00000117228 NA GBP1 guanylate binding protein 1, interferon-inducible 2633 ENSG00000117228
56  ENSG00000137496 NA IL18BP interleukin 18 binding protein 10068 ENSG00000137496
57  ENSG00000141574 NA SECTM1 secreted and transmembrane 1 6398 ENSG00000141574
58  ENSG00000140853 NA NLRC5 NLR family, CARD domain containing 5 84166 ENSG00000140853
59  ENSG00000130303 NA BST2 bone marrow stromal cell antigen 2 684 ENSG00000130303
60  ENSG00000115415 NA STAT1 signal transducer and activator of transcription 1, 91kDa 6772 ENSG00000115415
61  ENSG00000185507 NA IRF7 interferon regulatory factor 7 3665 ENSG00000185507
62  ENSG00000165949 NA IFI27 interferon, alpha-inducible protein 27 3429 ENSG00000165949
63  ENSG00000204252 NA HLA-DOA major histocompatibility complex, class II, DO alpha 3111 ENSG00000204252
64  ENSG00000115267 NA IFIH1 interferon induced with helicase C domain 1 64135 ENSG00000115267
65  ENSG00000126709 NA IFI6 interferon, alpha-inducible protein 6 2537 ENSG00000126709
66  ENSG00000125347 NA IRF1 interferon regulatory factor 1 3659 ENSG00000125347


Database:biological process       Name:defense response       ID:GO:0006952
C=1107; O=64; E=8.78; R=7.29; rawP=2.35e-41; adjP=1.21e-38
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000107201 NA DDX58 DEAD (Asp-Glu-Ala-Asp) box polypeptide 58 23586 ENSG00000107201
2  ENSG00000204287 NA HLA-DRA major histocompatibility complex, class II, DR alpha 3122 ENSG00000204287
3  ENSG00000204592 NA HLA-E major histocompatibility complex, class I, E 3133 ENSG00000204592
4  ENSG00000204642 NA HLA-F major histocompatibility complex, class I, F 3134 ENSG00000204642
5  ENSG00000006210 NA CX3CL1 chemokine (C-X3-C motif) ligand 1 6376 ENSG00000006210
6  ENSG00000168394 NA TAP1 transporter 1, ATP-binding cassette, sub-family B (MDR/TAP) 6890 ENSG00000168394
7  ENSG00000068079 NA IFI35 interferon-induced protein 35 3430 ENSG00000068079
8  ENSG00000089041 NA P2RX7 purinergic receptor P2X, ligand-gated ion channel, 7 5027 ENSG00000089041
9  ENSG00000166710 NA B2M beta-2-microglobulin 567 ENSG00000166710
10  ENSG00000143761 NA ARF1 ADP-ribosylation factor 1 375 ENSG00000143761
11  ENSG00000132274 NA TRIM22 tripartite motif containing 22 10346 ENSG00000132274
12  ENSG00000089127 NA OAS1 2'-5'-oligoadenylate synthetase 1, 40/46kDa 4938 ENSG00000089127
13  ENSG00000223865 NA HLA-DPB1 major histocompatibility complex, class II, DP beta 1 3115 ENSG00000223865
14  ENSG00000183486 NA MX2 myxovirus (influenza virus) resistance 2 (mouse) 4600 ENSG00000183486
15  ENSG00000185885 NA IFITM1 interferon induced transmembrane protein 1 8519 ENSG00000185885
16  ENSG00000137959 NA IFI44L interferon-induced protein 44-like 10964 ENSG00000137959
17  ENSG00000196126 NA HLA-DRB1 major histocompatibility complex, class II, DR beta 1 3123 ENSG00000196126
18  ENSG00000138755 NA CXCL9 chemokine (C-X-C motif) ligand 9 4283 ENSG00000138755
19  ENSG00000131203 NA IDO1 indoleamine 2,3-dioxygenase 1 3620 ENSG00000131203
20  ENSG00000231389 NA HLA-DPA1 major histocompatibility complex, class II, DP alpha 1 3113 ENSG00000231389
21  ENSG00000111335 NA OAS2 2'-5'-oligoadenylate synthetase 2, 69/71kDa 4939 ENSG00000111335
22  ENSG00000156587 NA UBE2L6 ubiquitin-conjugating enzyme E2L 6 9246 ENSG00000156587
23  ENSG00000108771 NA DHX58 DEXH (Asp-Glu-X-His) box polypeptide 58 79132 ENSG00000108771
24  ENSG00000204264 NA PSMB8 proteasome (prosome, macropain) subunit, beta type, 8 (large multifunctional peptidase 7) 5696 ENSG00000204264
25  ENSG00000164342 NA TLR3 toll-like receptor 3 7098 ENSG00000164342
26  ENSG00000213928 NA IRF9 interferon regulatory factor 9 10379 ENSG00000213928
27  ENSG00000162645 NA GBP2 guanylate binding protein 2, interferon-inducible 2634 ENSG00000162645
28  ENSG00000176171 NA BNIP3 BCL2/adenovirus E1B 19kDa interacting protein 3 664 ENSG00000176171
29  ENSG00000160710 NA ADAR adenosine deaminase, RNA-specific 103 ENSG00000160710
30  ENSG00000111331 NA OAS3 2'-5'-oligoadenylate synthetase 3, 100kDa 4940 ENSG00000111331
31  ENSG00000137752 NA CASP1 caspase 1, apoptosis-related cysteine peptidase 834 ENSG00000137752
32  ENSG00000239713 NA APOBEC3G apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3G 60489 ENSG00000239713
33  ENSG00000100342 NA APOL1 apolipoprotein L, 1 8542 ENSG00000100342
34  ENSG00000138496 NA PARP9 poly (ADP-ribose) polymerase family, member 9 83666 ENSG00000138496
35  ENSG00000157601 NA MX1 myxovirus (influenza virus) resistance 1, interferon-inducible protein p78 (mouse) 4599 ENSG00000157601
36  ENSG00000100448 NA CTSG cathepsin G 1511 ENSG00000100448
37  ENSG00000198574 NA SH2D1B SH2 domain containing 1B 117157 ENSG00000198574
38  ENSG00000128284 NA APOL3 apolipoprotein L, 3 80833 ENSG00000128284
39  ENSG00000196735 NA HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1 3117 ENSG00000196735
40  ENSG00000117226 NA GBP3 guanylate binding protein 3 2635 ENSG00000117226
41  ENSG00000184979 NA USP18 ubiquitin specific peptidase 18 11274 ENSG00000184979
42  ENSG00000119917 NA IFIT3 interferon-induced protein with tetratricopeptide repeats 3 3437 ENSG00000119917
43  ENSG00000135114 NA OASL 2'-5'-oligoadenylate synthetase-like 8638 ENSG00000135114
44  ENSG00000019582 NA CD74 CD74 molecule, major histocompatibility complex, class II invariant chain 972 ENSG00000019582
45  ENSG00000187608 NA ISG15 ISG15 ubiquitin-like modifier 9636 ENSG00000187608
46  ENSG00000179583 NA CIITA class II, major histocompatibility complex, transactivator 4261 ENSG00000179583
47  ENSG00000132530 NA XAF1 XIAP associated factor 1 54739 ENSG00000132530
48  ENSG00000170581 NA STAT2 signal transducer and activator of transcription 2, 113kDa 6773 ENSG00000170581
49  ENSG00000092009 NA CMA1 chymase 1, mast cell 1215 ENSG00000092009
50  ENSG00000169245 NA CXCL10 chemokine (C-X-C motif) ligand 10 3627 ENSG00000169245
51  ENSG00000119922 NA IFIT2 interferon-induced protein with tetratricopeptide repeats 2 3433 ENSG00000119922
52  ENSG00000169248 NA CXCL11 chemokine (C-X-C motif) ligand 11 6373 ENSG00000169248
53  ENSG00000134321 NA RSAD2 radical S-adenosyl methionine domain containing 2 91543 ENSG00000134321
54  ENSG00000117228 NA GBP1 guanylate binding protein 1, interferon-inducible 2633 ENSG00000117228
55  ENSG00000123609 NA NMI N-myc (and STAT) interactor 9111 ENSG00000123609
56  ENSG00000140853 NA NLRC5 NLR family, CARD domain containing 5 84166 ENSG00000140853
57  ENSG00000130303 NA BST2 bone marrow stromal cell antigen 2 684 ENSG00000130303
58  ENSG00000115415 NA STAT1 signal transducer and activator of transcription 1, 91kDa 6772 ENSG00000115415
59  ENSG00000172236 NA TPSAB1 tryptase alpha/beta 1 7177 ENSG00000172236
60  ENSG00000185507 NA IRF7 interferon regulatory factor 7 3665 ENSG00000185507
61  ENSG00000165949 NA IFI27 interferon, alpha-inducible protein 27 3429 ENSG00000165949
62  ENSG00000115267 NA IFIH1 interferon induced with helicase C domain 1 64135 ENSG00000115267
63  ENSG00000126709 NA IFI6 interferon, alpha-inducible protein 6 2537 ENSG00000126709
64  ENSG00000125347 NA IRF1 interferon regulatory factor 1 3659 ENSG00000125347


Database:biological process       Name:innate immune response       ID:GO:0045087
C=539; O=48; E=4.27; R=11.23; rawP=2.14e-38; adjP=7.38e-36
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000107201 NA DDX58 DEAD (Asp-Glu-Ala-Asp) box polypeptide 58 23586 ENSG00000107201
2  ENSG00000204287 NA HLA-DRA major histocompatibility complex, class II, DR alpha 3122 ENSG00000204287
3  ENSG00000204592 NA HLA-E major histocompatibility complex, class I, E 3133 ENSG00000204592
4  ENSG00000204642 NA HLA-F major histocompatibility complex, class I, F 3134 ENSG00000204642
5  ENSG00000168394 NA TAP1 transporter 1, ATP-binding cassette, sub-family B (MDR/TAP) 6890 ENSG00000168394
6  ENSG00000068079 NA IFI35 interferon-induced protein 35 3430 ENSG00000068079
7  ENSG00000089041 NA P2RX7 purinergic receptor P2X, ligand-gated ion channel, 7 5027 ENSG00000089041
8  ENSG00000166710 NA B2M beta-2-microglobulin 567 ENSG00000166710
9  ENSG00000089127 NA OAS1 2'-5'-oligoadenylate synthetase 1, 40/46kDa 4938 ENSG00000089127
10  ENSG00000223865 NA HLA-DPB1 major histocompatibility complex, class II, DP beta 1 3115 ENSG00000223865
11  ENSG00000183486 NA MX2 myxovirus (influenza virus) resistance 2 (mouse) 4600 ENSG00000183486
12  ENSG00000185885 NA IFITM1 interferon induced transmembrane protein 1 8519 ENSG00000185885
13  ENSG00000196126 NA HLA-DRB1 major histocompatibility complex, class II, DR beta 1 3123 ENSG00000196126
14  ENSG00000231389 NA HLA-DPA1 major histocompatibility complex, class II, DP alpha 1 3113 ENSG00000231389
15  ENSG00000111335 NA OAS2 2'-5'-oligoadenylate synthetase 2, 69/71kDa 4939 ENSG00000111335
16  ENSG00000156587 NA UBE2L6 ubiquitin-conjugating enzyme E2L 6 9246 ENSG00000156587
17  ENSG00000108771 NA DHX58 DEXH (Asp-Glu-X-His) box polypeptide 58 79132 ENSG00000108771
18  ENSG00000204264 NA PSMB8 proteasome (prosome, macropain) subunit, beta type, 8 (large multifunctional peptidase 7) 5696 ENSG00000204264
19  ENSG00000164342 NA TLR3 toll-like receptor 3 7098 ENSG00000164342
20  ENSG00000213928 NA IRF9 interferon regulatory factor 9 10379 ENSG00000213928
21  ENSG00000162645 NA GBP2 guanylate binding protein 2, interferon-inducible 2634 ENSG00000162645
22  ENSG00000160710 NA ADAR adenosine deaminase, RNA-specific 103 ENSG00000160710
23  ENSG00000111331 NA OAS3 2'-5'-oligoadenylate synthetase 3, 100kDa 4940 ENSG00000111331
24  ENSG00000137752 NA CASP1 caspase 1, apoptosis-related cysteine peptidase 834 ENSG00000137752
25  ENSG00000239713 NA APOBEC3G apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3G 60489 ENSG00000239713
26  ENSG00000100342 NA APOL1 apolipoprotein L, 1 8542 ENSG00000100342
27  ENSG00000138496 NA PARP9 poly (ADP-ribose) polymerase family, member 9 83666 ENSG00000138496
28  ENSG00000157601 NA MX1 myxovirus (influenza virus) resistance 1, interferon-inducible protein p78 (mouse) 4599 ENSG00000157601
29  ENSG00000198574 NA SH2D1B SH2 domain containing 1B 117157 ENSG00000198574
30  ENSG00000196735 NA HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1 3117 ENSG00000196735
31  ENSG00000184979 NA USP18 ubiquitin specific peptidase 18 11274 ENSG00000184979
32  ENSG00000119917 NA IFIT3 interferon-induced protein with tetratricopeptide repeats 3 3437 ENSG00000119917
33  ENSG00000135114 NA OASL 2'-5'-oligoadenylate synthetase-like 8638 ENSG00000135114
34  ENSG00000187608 NA ISG15 ISG15 ubiquitin-like modifier 9636 ENSG00000187608
35  ENSG00000179583 NA CIITA class II, major histocompatibility complex, transactivator 4261 ENSG00000179583
36  ENSG00000132530 NA XAF1 XIAP associated factor 1 54739 ENSG00000132530
37  ENSG00000170581 NA STAT2 signal transducer and activator of transcription 2, 113kDa 6773 ENSG00000170581
38  ENSG00000119922 NA IFIT2 interferon-induced protein with tetratricopeptide repeats 2 3433 ENSG00000119922
39  ENSG00000134321 NA RSAD2 radical S-adenosyl methionine domain containing 2 91543 ENSG00000134321
40  ENSG00000117228 NA GBP1 guanylate binding protein 1, interferon-inducible 2633 ENSG00000117228
41  ENSG00000140853 NA NLRC5 NLR family, CARD domain containing 5 84166 ENSG00000140853
42  ENSG00000130303 NA BST2 bone marrow stromal cell antigen 2 684 ENSG00000130303
43  ENSG00000115415 NA STAT1 signal transducer and activator of transcription 1, 91kDa 6772 ENSG00000115415
44  ENSG00000185507 NA IRF7 interferon regulatory factor 7 3665 ENSG00000185507
45  ENSG00000165949 NA IFI27 interferon, alpha-inducible protein 27 3429 ENSG00000165949
46  ENSG00000115267 NA IFIH1 interferon induced with helicase C domain 1 64135 ENSG00000115267
47  ENSG00000126709 NA IFI6 interferon, alpha-inducible protein 6 2537 ENSG00000126709
48  ENSG00000125347 NA IRF1 interferon regulatory factor 1 3659 ENSG00000125347


Database:biological process       Name:type I interferon-mediated signaling pathway       ID:GO:0060337
C=72; O=26; E=0.57; R=45.54; rawP=2.48e-37; adjP=5.13e-35
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000157601 NA MX1 myxovirus (influenza virus) resistance 1, interferon-inducible protein p78 (mouse) 4599 ENSG00000157601
2  ENSG00000204592 NA HLA-E major histocompatibility complex, class I, E 3133 ENSG00000204592
3  ENSG00000204642 NA HLA-F major histocompatibility complex, class I, F 3134 ENSG00000204642
4  ENSG00000184979 NA USP18 ubiquitin specific peptidase 18 11274 ENSG00000184979
5  ENSG00000068079 NA IFI35 interferon-induced protein 35 3430 ENSG00000068079
6  ENSG00000119917 NA IFIT3 interferon-induced protein with tetratricopeptide repeats 3 3437 ENSG00000119917
7  ENSG00000135114 NA OASL 2'-5'-oligoadenylate synthetase-like 8638 ENSG00000135114
8  ENSG00000089127 NA OAS1 2'-5'-oligoadenylate synthetase 1, 40/46kDa 4938 ENSG00000089127
9  ENSG00000183486 NA MX2 myxovirus (influenza virus) resistance 2 (mouse) 4600 ENSG00000183486
10  ENSG00000187608 NA ISG15 ISG15 ubiquitin-like modifier 9636 ENSG00000187608
11  ENSG00000132530 NA XAF1 XIAP associated factor 1 54739 ENSG00000132530
12  ENSG00000185885 NA IFITM1 interferon induced transmembrane protein 1 8519 ENSG00000185885
13  ENSG00000170581 NA STAT2 signal transducer and activator of transcription 2, 113kDa 6773 ENSG00000170581
14  ENSG00000111335 NA OAS2 2'-5'-oligoadenylate synthetase 2, 69/71kDa 4939 ENSG00000111335
15  ENSG00000119922 NA IFIT2 interferon-induced protein with tetratricopeptide repeats 2 3433 ENSG00000119922
16  ENSG00000204264 NA PSMB8 proteasome (prosome, macropain) subunit, beta type, 8 (large multifunctional peptidase 7) 5696 ENSG00000204264
17  ENSG00000140853 NA NLRC5 NLR family, CARD domain containing 5 84166 ENSG00000140853
18  ENSG00000213928 NA IRF9 interferon regulatory factor 9 10379 ENSG00000213928
19  ENSG00000162645 NA GBP2 guanylate binding protein 2, interferon-inducible 2634 ENSG00000162645
20  ENSG00000115415 NA STAT1 signal transducer and activator of transcription 1, 91kDa 6772 ENSG00000115415
21  ENSG00000160710 NA ADAR adenosine deaminase, RNA-specific 103 ENSG00000160710
22  ENSG00000185507 NA IRF7 interferon regulatory factor 7 3665 ENSG00000185507
23  ENSG00000165949 NA IFI27 interferon, alpha-inducible protein 27 3429 ENSG00000165949
24  ENSG00000111331 NA OAS3 2'-5'-oligoadenylate synthetase 3, 100kDa 4940 ENSG00000111331
25  ENSG00000126709 NA IFI6 interferon, alpha-inducible protein 6 2537 ENSG00000126709
26  ENSG00000125347 NA IRF1 interferon regulatory factor 1 3659 ENSG00000125347


Database:biological process       Name:cellular response to type I interferon       ID:GO:0071357
C=72; O=26; E=0.57; R=45.54; rawP=2.48e-37; adjP=5.13e-35
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000157601 NA MX1 myxovirus (influenza virus) resistance 1, interferon-inducible protein p78 (mouse) 4599 ENSG00000157601
2  ENSG00000204592 NA HLA-E major histocompatibility complex, class I, E 3133 ENSG00000204592
3  ENSG00000204642 NA HLA-F major histocompatibility complex, class I, F 3134 ENSG00000204642
4  ENSG00000184979 NA USP18 ubiquitin specific peptidase 18 11274 ENSG00000184979
5  ENSG00000068079 NA IFI35 interferon-induced protein 35 3430 ENSG00000068079
6  ENSG00000119917 NA IFIT3 interferon-induced protein with tetratricopeptide repeats 3 3437 ENSG00000119917
7  ENSG00000135114 NA OASL 2'-5'-oligoadenylate synthetase-like 8638 ENSG00000135114
8  ENSG00000089127 NA OAS1 2'-5'-oligoadenylate synthetase 1, 40/46kDa 4938 ENSG00000089127
9  ENSG00000183486 NA MX2 myxovirus (influenza virus) resistance 2 (mouse) 4600 ENSG00000183486
10  ENSG00000187608 NA ISG15 ISG15 ubiquitin-like modifier 9636 ENSG00000187608
11  ENSG00000132530 NA XAF1 XIAP associated factor 1 54739 ENSG00000132530
12  ENSG00000185885 NA IFITM1 interferon induced transmembrane protein 1 8519 ENSG00000185885
13  ENSG00000170581 NA STAT2 signal transducer and activator of transcription 2, 113kDa 6773 ENSG00000170581
14  ENSG00000111335 NA OAS2 2'-5'-oligoadenylate synthetase 2, 69/71kDa 4939 ENSG00000111335
15  ENSG00000119922 NA IFIT2 interferon-induced protein with tetratricopeptide repeats 2 3433 ENSG00000119922
16  ENSG00000204264 NA PSMB8 proteasome (prosome, macropain) subunit, beta type, 8 (large multifunctional peptidase 7) 5696 ENSG00000204264
17  ENSG00000140853 NA NLRC5 NLR family, CARD domain containing 5 84166 ENSG00000140853
18  ENSG00000213928 NA IRF9 interferon regulatory factor 9 10379 ENSG00000213928
19  ENSG00000162645 NA GBP2 guanylate binding protein 2, interferon-inducible 2634 ENSG00000162645
20  ENSG00000115415 NA STAT1 signal transducer and activator of transcription 1, 91kDa 6772 ENSG00000115415
21  ENSG00000160710 NA ADAR adenosine deaminase, RNA-specific 103 ENSG00000160710
22  ENSG00000185507 NA IRF7 interferon regulatory factor 7 3665 ENSG00000185507
23  ENSG00000165949 NA IFI27 interferon, alpha-inducible protein 27 3429 ENSG00000165949
24  ENSG00000111331 NA OAS3 2'-5'-oligoadenylate synthetase 3, 100kDa 4940 ENSG00000111331
25  ENSG00000126709 NA IFI6 interferon, alpha-inducible protein 6 2537 ENSG00000126709
26  ENSG00000125347 NA IRF1 interferon regulatory factor 1 3659 ENSG00000125347


Database:biological process       Name:response to type I interferon       ID:GO:0034340
C=73; O=26; E=0.58; R=44.92; rawP=3.82e-37; adjP=6.58e-35
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000157601 NA MX1 myxovirus (influenza virus) resistance 1, interferon-inducible protein p78 (mouse) 4599 ENSG00000157601
2  ENSG00000204592 NA HLA-E major histocompatibility complex, class I, E 3133 ENSG00000204592
3  ENSG00000204642 NA HLA-F major histocompatibility complex, class I, F 3134 ENSG00000204642
4  ENSG00000184979 NA USP18 ubiquitin specific peptidase 18 11274 ENSG00000184979
5  ENSG00000068079 NA IFI35 interferon-induced protein 35 3430 ENSG00000068079
6  ENSG00000119917 NA IFIT3 interferon-induced protein with tetratricopeptide repeats 3 3437 ENSG00000119917
7  ENSG00000135114 NA OASL 2'-5'-oligoadenylate synthetase-like 8638 ENSG00000135114
8  ENSG00000089127 NA OAS1 2'-5'-oligoadenylate synthetase 1, 40/46kDa 4938 ENSG00000089127
9  ENSG00000183486 NA MX2 myxovirus (influenza virus) resistance 2 (mouse) 4600 ENSG00000183486
10  ENSG00000187608 NA ISG15 ISG15 ubiquitin-like modifier 9636 ENSG00000187608
11  ENSG00000132530 NA XAF1 XIAP associated factor 1 54739 ENSG00000132530
12  ENSG00000185885 NA IFITM1 interferon induced transmembrane protein 1 8519 ENSG00000185885
13  ENSG00000170581 NA STAT2 signal transducer and activator of transcription 2, 113kDa 6773 ENSG00000170581
14  ENSG00000111335 NA OAS2 2'-5'-oligoadenylate synthetase 2, 69/71kDa 4939 ENSG00000111335
15  ENSG00000119922 NA IFIT2 interferon-induced protein with tetratricopeptide repeats 2 3433 ENSG00000119922
16  ENSG00000204264 NA PSMB8 proteasome (prosome, macropain) subunit, beta type, 8 (large multifunctional peptidase 7) 5696 ENSG00000204264
17  ENSG00000140853 NA NLRC5 NLR family, CARD domain containing 5 84166 ENSG00000140853
18  ENSG00000213928 NA IRF9 interferon regulatory factor 9 10379 ENSG00000213928
19  ENSG00000162645 NA GBP2 guanylate binding protein 2, interferon-inducible 2634 ENSG00000162645
20  ENSG00000115415 NA STAT1 signal transducer and activator of transcription 1, 91kDa 6772 ENSG00000115415
21  ENSG00000160710 NA ADAR adenosine deaminase, RNA-specific 103 ENSG00000160710
22  ENSG00000185507 NA IRF7 interferon regulatory factor 7 3665 ENSG00000185507
23  ENSG00000165949 NA IFI27 interferon, alpha-inducible protein 27 3429 ENSG00000165949
24  ENSG00000111331 NA OAS3 2'-5'-oligoadenylate synthetase 3, 100kDa 4940 ENSG00000111331
25  ENSG00000126709 NA IFI6 interferon, alpha-inducible protein 6 2537 ENSG00000126709
26  ENSG00000125347 NA IRF1 interferon regulatory factor 1 3659 ENSG00000125347


Database:biological process       Name:immune system process       ID:GO:0002376
C=1792; O=72; E=14.21; R=5.07; rawP=5.50e-37; adjP=8.12e-35
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000006210 NA CX3CL1 chemokine (C-X3-C motif) ligand 1 6376 ENSG00000006210
2  ENSG00000168394 NA TAP1 transporter 1, ATP-binding cassette, sub-family B (MDR/TAP) 6890 ENSG00000168394
3  ENSG00000089041 NA P2RX7 purinergic receptor P2X, ligand-gated ion channel, 7 5027 ENSG00000089041
4  ENSG00000131203 NA IDO1 indoleamine 2,3-dioxygenase 1 3620 ENSG00000131203
5  ENSG00000231389 NA HLA-DPA1 major histocompatibility complex, class II, DP alpha 1 3113 ENSG00000231389
6  ENSG00000124508 NA BTN2A2 butyrophilin, subfamily 2, member A2 10385 ENSG00000124508
7  ENSG00000204264 NA PSMB8 proteasome (prosome, macropain) subunit, beta type, 8 (large multifunctional peptidase 7) 5696 ENSG00000204264
8  ENSG00000164342 NA TLR3 toll-like receptor 3 7098 ENSG00000164342
9  ENSG00000162645 NA GBP2 guanylate binding protein 2, interferon-inducible 2634 ENSG00000162645
10  ENSG00000204267 NA TAP2 transporter 2, ATP-binding cassette, sub-family B (MDR/TAP) 6891 ENSG00000204267 ENSG00000250264
11  ENSG00000160710 NA ADAR adenosine deaminase, RNA-specific 103 ENSG00000160710
12  ENSG00000111331 NA OAS3 2'-5'-oligoadenylate synthetase 3, 100kDa 4940 ENSG00000111331
13  ENSG00000239713 NA APOBEC3G apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3G 60489 ENSG00000239713
14  ENSG00000157601 NA MX1 myxovirus (influenza virus) resistance 1, interferon-inducible protein p78 (mouse) 4599 ENSG00000157601
15  ENSG00000100448 NA CTSG cathepsin G 1511 ENSG00000100448
16  ENSG00000198574 NA SH2D1B SH2 domain containing 1B 117157 ENSG00000198574
17  ENSG00000184979 NA USP18 ubiquitin specific peptidase 18 11274 ENSG00000184979
18  ENSG00000242574 NA HLA-DMB major histocompatibility complex, class II, DM beta 3109 ENSG00000242574
19  ENSG00000121858 NA TNFSF10 tumor necrosis factor (ligand) superfamily, member 10 8743 ENSG00000121858
20  ENSG00000240065 NA PSMB9 proteasome (prosome, macropain) subunit, beta type, 9 (large multifunctional peptidase 2) 5698 ENSG00000240065
21  ENSG00000170581 NA STAT2 signal transducer and activator of transcription 2, 113kDa 6773 ENSG00000170581
22  ENSG00000204257 NA HLA-DMA major histocompatibility complex, class II, DM alpha 3108 ENSG00000204257
23  ENSG00000119922 NA IFIT2 interferon-induced protein with tetratricopeptide repeats 2 3433 ENSG00000119922
24  ENSG00000169245 NA CXCL10 chemokine (C-X-C motif) ligand 10 3627 ENSG00000169245
25  ENSG00000169248 NA CXCL11 chemokine (C-X-C motif) ligand 11 6373 ENSG00000169248
26  ENSG00000117228 NA GBP1 guanylate binding protein 1, interferon-inducible 2633 ENSG00000117228
27  ENSG00000141574 NA SECTM1 secreted and transmembrane 1 6398 ENSG00000141574
28  ENSG00000130303 NA BST2 bone marrow stromal cell antigen 2 684 ENSG00000130303
29  ENSG00000115415 NA STAT1 signal transducer and activator of transcription 1, 91kDa 6772 ENSG00000115415
30  ENSG00000185507 NA IRF7 interferon regulatory factor 7 3665 ENSG00000185507
31  ENSG00000204287 NA HLA-DRA major histocompatibility complex, class II, DR alpha 3122 ENSG00000204287
32  ENSG00000107201 NA DDX58 DEAD (Asp-Glu-Ala-Asp) box polypeptide 58 23586 ENSG00000107201
33  ENSG00000204642 NA HLA-F major histocompatibility complex, class I, F 3134 ENSG00000204642
34  ENSG00000204592 NA HLA-E major histocompatibility complex, class I, E 3133 ENSG00000204592
35  ENSG00000068079 NA IFI35 interferon-induced protein 35 3430 ENSG00000068079
36  ENSG00000166710 NA B2M beta-2-microglobulin 567 ENSG00000166710
37  ENSG00000132274 NA TRIM22 tripartite motif containing 22 10346 ENSG00000132274
38  ENSG00000143761 NA ARF1 ADP-ribosylation factor 1 375 ENSG00000143761
39  ENSG00000089127 NA OAS1 2'-5'-oligoadenylate synthetase 1, 40/46kDa 4938 ENSG00000089127
40  ENSG00000183486 NA MX2 myxovirus (influenza virus) resistance 2 (mouse) 4600 ENSG00000183486
41  ENSG00000223865 NA HLA-DPB1 major histocompatibility complex, class II, DP beta 1 3115 ENSG00000223865
42  ENSG00000185885 NA IFITM1 interferon induced transmembrane protein 1 8519 ENSG00000185885
43  ENSG00000137959 NA IFI44L interferon-induced protein 44-like 10964 ENSG00000137959
44  ENSG00000138755 NA CXCL9 chemokine (C-X-C motif) ligand 9 4283 ENSG00000138755
45  ENSG00000196126 NA HLA-DRB1 major histocompatibility complex, class II, DR beta 1 3123 ENSG00000196126
46  ENSG00000111335 NA OAS2 2'-5'-oligoadenylate synthetase 2, 69/71kDa 4939 ENSG00000111335
47  ENSG00000108771 NA DHX58 DEXH (Asp-Glu-X-His) box polypeptide 58 79132 ENSG00000108771
48  ENSG00000156587 NA UBE2L6 ubiquitin-conjugating enzyme E2L 6 9246 ENSG00000156587
49  ENSG00000197646 NA PDCD1LG2 programmed cell death 1 ligand 2 80380 ENSG00000197646
50  ENSG00000213928 NA IRF9 interferon regulatory factor 9 10379 ENSG00000213928
51  ENSG00000176171 NA BNIP3 BCL2/adenovirus E1B 19kDa interacting protein 3 664 ENSG00000176171
52  ENSG00000137752 NA CASP1 caspase 1, apoptosis-related cysteine peptidase 834 ENSG00000137752
53  ENSG00000100342 NA APOL1 apolipoprotein L, 1 8542 ENSG00000100342
54  ENSG00000138496 NA PARP9 poly (ADP-ribose) polymerase family, member 9 83666 ENSG00000138496
55  ENSG00000196735 NA HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1 3117 ENSG00000196735
56  ENSG00000117226 NA GBP3 guanylate binding protein 3 2635 ENSG00000117226
57  ENSG00000090554 NA FLT3LG fms-related tyrosine kinase 3 ligand 2323 ENSG00000090554
58  ENSG00000135114 NA OASL 2'-5'-oligoadenylate synthetase-like 8638 ENSG00000135114
59  ENSG00000119917 NA IFIT3 interferon-induced protein with tetratricopeptide repeats 3 3437 ENSG00000119917
60  ENSG00000132530 NA XAF1 XIAP associated factor 1 54739 ENSG00000132530
61  ENSG00000179583 NA CIITA class II, major histocompatibility complex, transactivator 4261 ENSG00000179583
62  ENSG00000187608 NA ISG15 ISG15 ubiquitin-like modifier 9636 ENSG00000187608
63  ENSG00000019582 NA CD74 CD74 molecule, major histocompatibility complex, class II invariant chain 972 ENSG00000019582
64  ENSG00000205220 NA PSMB10 proteasome (prosome, macropain) subunit, beta type, 10 5699 ENSG00000205220
65  ENSG00000134321 NA RSAD2 radical S-adenosyl methionine domain containing 2 91543 ENSG00000134321
66  ENSG00000137496 NA IL18BP interleukin 18 binding protein 10068 ENSG00000137496
67  ENSG00000140853 NA NLRC5 NLR family, CARD domain containing 5 84166 ENSG00000140853
68  ENSG00000165949 NA IFI27 interferon, alpha-inducible protein 27 3429 ENSG00000165949
69  ENSG00000204252 NA HLA-DOA major histocompatibility complex, class II, DO alpha 3111 ENSG00000204252
70  ENSG00000115267 NA IFIH1 interferon induced with helicase C domain 1 64135 ENSG00000115267
71  ENSG00000126709 NA IFI6 interferon, alpha-inducible protein 6 2537 ENSG00000126709
72  ENSG00000125347 NA IRF1 interferon regulatory factor 1 3659 ENSG00000125347


Database:biological process       Name:defense response to virus       ID:GO:0051607
C=182; O=32; E=1.44; R=22.18; rawP=1.03e-34; adjP=1.33e-32
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000107201 NA DDX58 DEAD (Asp-Glu-Ala-Asp) box polypeptide 58 23586 ENSG00000107201
2  ENSG00000157601 NA MX1 myxovirus (influenza virus) resistance 1, interferon-inducible protein p78 (mouse) 4599 ENSG00000157601
3  ENSG00000117226 NA GBP3 guanylate binding protein 3 2635 ENSG00000117226
4  ENSG00000166710 NA B2M beta-2-microglobulin 567 ENSG00000166710
5  ENSG00000143761 NA ARF1 ADP-ribosylation factor 1 375 ENSG00000143761
6  ENSG00000132274 NA TRIM22 tripartite motif containing 22 10346 ENSG00000132274
7  ENSG00000119917 NA IFIT3 interferon-induced protein with tetratricopeptide repeats 3 3437 ENSG00000119917
8  ENSG00000135114 NA OASL 2'-5'-oligoadenylate synthetase-like 8638 ENSG00000135114
9  ENSG00000089127 NA OAS1 2'-5'-oligoadenylate synthetase 1, 40/46kDa 4938 ENSG00000089127
10  ENSG00000183486 NA MX2 myxovirus (influenza virus) resistance 2 (mouse) 4600 ENSG00000183486
11  ENSG00000187608 NA ISG15 ISG15 ubiquitin-like modifier 9636 ENSG00000187608
12  ENSG00000185885 NA IFITM1 interferon induced transmembrane protein 1 8519 ENSG00000185885
13  ENSG00000170581 NA STAT2 signal transducer and activator of transcription 2, 113kDa 6773 ENSG00000170581
14  ENSG00000137959 NA IFI44L interferon-induced protein 44-like 10964 ENSG00000137959
15  ENSG00000138755 NA CXCL9 chemokine (C-X-C motif) ligand 9 4283 ENSG00000138755
16  ENSG00000111335 NA OAS2 2'-5'-oligoadenylate synthetase 2, 69/71kDa 4939 ENSG00000111335
17  ENSG00000119922 NA IFIT2 interferon-induced protein with tetratricopeptide repeats 2 3433 ENSG00000119922
18  ENSG00000169245 NA CXCL10 chemokine (C-X-C motif) ligand 10 3627 ENSG00000169245
19  ENSG00000108771 NA DHX58 DEXH (Asp-Glu-X-His) box polypeptide 58 79132 ENSG00000108771
20  ENSG00000164342 NA TLR3 toll-like receptor 3 7098 ENSG00000164342
21  ENSG00000134321 NA RSAD2 radical S-adenosyl methionine domain containing 2 91543 ENSG00000134321
22  ENSG00000117228 NA GBP1 guanylate binding protein 1, interferon-inducible 2633 ENSG00000117228
23  ENSG00000140853 NA NLRC5 NLR family, CARD domain containing 5 84166 ENSG00000140853
24  ENSG00000213928 NA IRF9 interferon regulatory factor 9 10379 ENSG00000213928
25  ENSG00000130303 NA BST2 bone marrow stromal cell antigen 2 684 ENSG00000130303
26  ENSG00000115415 NA STAT1 signal transducer and activator of transcription 1, 91kDa 6772 ENSG00000115415
27  ENSG00000176171 NA BNIP3 BCL2/adenovirus E1B 19kDa interacting protein 3 664 ENSG00000176171
28  ENSG00000185507 NA IRF7 interferon regulatory factor 7 3665 ENSG00000185507
29  ENSG00000111331 NA OAS3 2'-5'-oligoadenylate synthetase 3, 100kDa 4940 ENSG00000111331
30  ENSG00000115267 NA IFIH1 interferon induced with helicase C domain 1 64135 ENSG00000115267
31  ENSG00000239713 NA APOBEC3G apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3G 60489 ENSG00000239713
32  ENSG00000125347 NA IRF1 interferon regulatory factor 1 3659 ENSG00000125347


Database:biological process       Name:response to virus       ID:GO:0009615
C=260; O=35; E=2.06; R=16.98; rawP=8.67e-34; adjP=9.96e-32
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000107201 NA DDX58 DEAD (Asp-Glu-Ala-Asp) box polypeptide 58 23586 ENSG00000107201
2  ENSG00000137965 NA IFI44 interferon-induced protein 44 10561 ENSG00000137965
3  ENSG00000068079 NA IFI35 interferon-induced protein 35 3430 ENSG00000068079
4  ENSG00000166710 NA B2M beta-2-microglobulin 567 ENSG00000166710
5  ENSG00000143761 NA ARF1 ADP-ribosylation factor 1 375 ENSG00000143761
6  ENSG00000132274 NA TRIM22 tripartite motif containing 22 10346 ENSG00000132274
7  ENSG00000089127 NA OAS1 2'-5'-oligoadenylate synthetase 1, 40/46kDa 4938 ENSG00000089127
8  ENSG00000183486 NA MX2 myxovirus (influenza virus) resistance 2 (mouse) 4600 ENSG00000183486
9  ENSG00000185885 NA IFITM1 interferon induced transmembrane protein 1 8519 ENSG00000185885
10  ENSG00000137959 NA IFI44L interferon-induced protein 44-like 10964 ENSG00000137959
11  ENSG00000138755 NA CXCL9 chemokine (C-X-C motif) ligand 9 4283 ENSG00000138755
12  ENSG00000111335 NA OAS2 2'-5'-oligoadenylate synthetase 2, 69/71kDa 4939 ENSG00000111335
13  ENSG00000108771 NA DHX58 DEXH (Asp-Glu-X-His) box polypeptide 58 79132 ENSG00000108771
14  ENSG00000164342 NA TLR3 toll-like receptor 3 7098 ENSG00000164342
15  ENSG00000213928 NA IRF9 interferon regulatory factor 9 10379 ENSG00000213928
16  ENSG00000176171 NA BNIP3 BCL2/adenovirus E1B 19kDa interacting protein 3 664 ENSG00000176171
17  ENSG00000160710 NA ADAR adenosine deaminase, RNA-specific 103 ENSG00000160710
18  ENSG00000111331 NA OAS3 2'-5'-oligoadenylate synthetase 3, 100kDa 4940 ENSG00000111331
19  ENSG00000239713 NA APOBEC3G apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3G 60489 ENSG00000239713
20  ENSG00000157601 NA MX1 myxovirus (influenza virus) resistance 1, interferon-inducible protein p78 (mouse) 4599 ENSG00000157601
21  ENSG00000117226 NA GBP3 guanylate binding protein 3 2635 ENSG00000117226
22  ENSG00000135114 NA OASL 2'-5'-oligoadenylate synthetase-like 8638 ENSG00000135114
23  ENSG00000119917 NA IFIT3 interferon-induced protein with tetratricopeptide repeats 3 3437 ENSG00000119917
24  ENSG00000170581 NA STAT2 signal transducer and activator of transcription 2, 113kDa 6773 ENSG00000170581
25  ENSG00000187608 NA ISG15 ISG15 ubiquitin-like modifier 9636 ENSG00000187608
26  ENSG00000169245 NA CXCL10 chemokine (C-X-C motif) ligand 10 3627 ENSG00000169245
27  ENSG00000119922 NA IFIT2 interferon-induced protein with tetratricopeptide repeats 2 3433 ENSG00000119922
28  ENSG00000134321 NA RSAD2 radical S-adenosyl methionine domain containing 2 91543 ENSG00000134321
29  ENSG00000117228 NA GBP1 guanylate binding protein 1, interferon-inducible 2633 ENSG00000117228
30  ENSG00000115415 NA STAT1 signal transducer and activator of transcription 1, 91kDa 6772 ENSG00000115415
31  ENSG00000130303 NA BST2 bone marrow stromal cell antigen 2 684 ENSG00000130303
32  ENSG00000140853 NA NLRC5 NLR family, CARD domain containing 5 84166 ENSG00000140853
33  ENSG00000185507 NA IRF7 interferon regulatory factor 7 3665 ENSG00000185507
34  ENSG00000115267 NA IFIH1 interferon induced with helicase C domain 1 64135 ENSG00000115267
35  ENSG00000125347 NA IRF1 interferon regulatory factor 1 3659 ENSG00000125347


Database:biological process       Name:cytokine-mediated signaling pathway       ID:GO:0019221
C=339; O=37; E=2.69; R=13.77; rawP=2.39e-32; adjP=2.47e-30
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000204287 NA HLA-DRA major histocompatibility complex, class II, DR alpha 3122 ENSG00000204287
2  ENSG00000204592 NA HLA-E major histocompatibility complex, class I, E 3133 ENSG00000204592
3  ENSG00000204642 NA HLA-F major histocompatibility complex, class I, F 3134 ENSG00000204642
4  ENSG00000006210 NA CX3CL1 chemokine (C-X3-C motif) ligand 1 6376 ENSG00000006210
5  ENSG00000068079 NA IFI35 interferon-induced protein 35 3430 ENSG00000068079
6  ENSG00000166710 NA B2M beta-2-microglobulin 567 ENSG00000166710
7  ENSG00000089127 NA OAS1 2'-5'-oligoadenylate synthetase 1, 40/46kDa 4938 ENSG00000089127
8  ENSG00000223865 NA HLA-DPB1 major histocompatibility complex, class II, DP beta 1 3115 ENSG00000223865
9  ENSG00000183486 NA MX2 myxovirus (influenza virus) resistance 2 (mouse) 4600 ENSG00000183486
10  ENSG00000185885 NA IFITM1 interferon induced transmembrane protein 1 8519 ENSG00000185885
11  ENSG00000196126 NA HLA-DRB1 major histocompatibility complex, class II, DR beta 1 3123 ENSG00000196126
12  ENSG00000231389 NA HLA-DPA1 major histocompatibility complex, class II, DP alpha 1 3113 ENSG00000231389
13  ENSG00000111335 NA OAS2 2'-5'-oligoadenylate synthetase 2, 69/71kDa 4939 ENSG00000111335
14  ENSG00000156587 NA UBE2L6 ubiquitin-conjugating enzyme E2L 6 9246 ENSG00000156587
15  ENSG00000204264 NA PSMB8 proteasome (prosome, macropain) subunit, beta type, 8 (large multifunctional peptidase 7) 5696 ENSG00000204264
16  ENSG00000213928 NA IRF9 interferon regulatory factor 9 10379 ENSG00000213928
17  ENSG00000162645 NA GBP2 guanylate binding protein 2, interferon-inducible 2634 ENSG00000162645
18  ENSG00000160710 NA ADAR adenosine deaminase, RNA-specific 103 ENSG00000160710
19  ENSG00000111331 NA OAS3 2'-5'-oligoadenylate synthetase 3, 100kDa 4940 ENSG00000111331
20  ENSG00000157601 NA MX1 myxovirus (influenza virus) resistance 1, interferon-inducible protein p78 (mouse) 4599 ENSG00000157601
21  ENSG00000196735 NA HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1 3117 ENSG00000196735
22  ENSG00000184979 NA USP18 ubiquitin specific peptidase 18 11274 ENSG00000184979
23  ENSG00000135114 NA OASL 2'-5'-oligoadenylate synthetase-like 8638 ENSG00000135114
24  ENSG00000119917 NA IFIT3 interferon-induced protein with tetratricopeptide repeats 3 3437 ENSG00000119917
25  ENSG00000019582 NA CD74 CD74 molecule, major histocompatibility complex, class II invariant chain 972 ENSG00000019582
26  ENSG00000170581 NA STAT2 signal transducer and activator of transcription 2, 113kDa 6773 ENSG00000170581
27  ENSG00000132530 NA XAF1 XIAP associated factor 1 54739 ENSG00000132530
28  ENSG00000179583 NA CIITA class II, major histocompatibility complex, transactivator 4261 ENSG00000179583
29  ENSG00000187608 NA ISG15 ISG15 ubiquitin-like modifier 9636 ENSG00000187608
30  ENSG00000119922 NA IFIT2 interferon-induced protein with tetratricopeptide repeats 2 3433 ENSG00000119922
31  ENSG00000117228 NA GBP1 guanylate binding protein 1, interferon-inducible 2633 ENSG00000117228
32  ENSG00000140853 NA NLRC5 NLR family, CARD domain containing 5 84166 ENSG00000140853
33  ENSG00000115415 NA STAT1 signal transducer and activator of transcription 1, 91kDa 6772 ENSG00000115415
34  ENSG00000185507 NA IRF7 interferon regulatory factor 7 3665 ENSG00000185507
35  ENSG00000165949 NA IFI27 interferon, alpha-inducible protein 27 3429 ENSG00000165949
36  ENSG00000126709 NA IFI6 interferon, alpha-inducible protein 6 2537 ENSG00000126709
37  ENSG00000125347 NA IRF1 interferon regulatory factor 1 3659 ENSG00000125347


Database:molecular function       Name:double-stranded RNA binding       ID:GO:0003725
C=44; O=9; E=0.31; R=28.95; rawP=1.81e-11; adjP=3.08e-09
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000107201 NA DDX58 DEAD (Asp-Glu-Ala-Asp) box polypeptide 58 23586 ENSG00000107201
2  ENSG00000111335 NA OAS2 2'-5'-oligoadenylate synthetase 2, 69/71kDa 4939 ENSG00000111335
3  ENSG00000108771 NA DHX58 DEXH (Asp-Glu-X-His) box polypeptide 58 79132 ENSG00000108771
4  ENSG00000164342 NA TLR3 toll-like receptor 3 7098 ENSG00000164342
5  ENSG00000160710 NA ADAR adenosine deaminase, RNA-specific 103 ENSG00000160710
6  ENSG00000111331 NA OAS3 2'-5'-oligoadenylate synthetase 3, 100kDa 4940 ENSG00000111331
7  ENSG00000135114 NA OASL 2'-5'-oligoadenylate synthetase-like 8638 ENSG00000135114
8  ENSG00000089127 NA OAS1 2'-5'-oligoadenylate synthetase 1, 40/46kDa 4938 ENSG00000089127
9  ENSG00000115267 NA IFIH1 interferon induced with helicase C domain 1 64135 ENSG00000115267


Database:molecular function       Name:2'-5'-oligoadenylate synthetase activity       ID:GO:0001730
C=4; O=4; E=0.03; R=141.52; rawP=2.36e-09; adjP=2.01e-07
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000111335 NA OAS2 2'-5'-oligoadenylate synthetase 2, 69/71kDa 4939 ENSG00000111335
2  ENSG00000111331 NA OAS3 2'-5'-oligoadenylate synthetase 3, 100kDa 4940 ENSG00000111331
3  ENSG00000135114 NA OASL 2'-5'-oligoadenylate synthetase-like 8638 ENSG00000135114
4  ENSG00000089127 NA OAS1 2'-5'-oligoadenylate synthetase 1, 40/46kDa 4938 ENSG00000089127


Database:molecular function       Name:       ID:GO:0032395
C=12; O=5; E=0.08; R=58.97; rawP=1.22e-08; adjP=6.91e-07
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000196126 NA HLA-DRB1 major histocompatibility complex, class II, DR beta 1 3123 ENSG00000196126
2  ENSG00000204287 NA HLA-DRA major histocompatibility complex, class II, DR alpha 3122 ENSG00000204287
3  ENSG00000231389 NA HLA-DPA1 major histocompatibility complex, class II, DP alpha 1 3113 ENSG00000231389
4  ENSG00000204252 NA HLA-DOA major histocompatibility complex, class II, DO alpha 3111 ENSG00000204252
5  ENSG00000196735 NA HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1 3117 ENSG00000196735


Database:molecular function       Name:adenylyltransferase activity       ID:GO:0070566
C=20; O=4; E=0.14; R=28.30; rawP=1.05e-05; adjP=0.0004
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000111335 NA OAS2 2'-5'-oligoadenylate synthetase 2, 69/71kDa 4939 ENSG00000111335
2  ENSG00000111331 NA OAS3 2'-5'-oligoadenylate synthetase 3, 100kDa 4940 ENSG00000111331
3  ENSG00000135114 NA OASL 2'-5'-oligoadenylate synthetase-like 8638 ENSG00000135114
4  ENSG00000089127 NA OAS1 2'-5'-oligoadenylate synthetase 1, 40/46kDa 4938 ENSG00000089127


Database:molecular function       Name:NAD+ ADP-ribosyltransferase activity       ID:GO:0003950
C=26; O=4; E=0.18; R=21.77; rawP=3.13e-05; adjP=0.0009
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000059378 NA PARP12 poly (ADP-ribose) polymerase family, member 12 64761 ENSG00000059378
2  ENSG00000178685 NA PARP10 poly (ADP-ribose) polymerase family, member 10 84875 ENSG00000178685
3  ENSG00000173193 NA PARP14 poly (ADP-ribose) polymerase family, member 14 54625 ENSG00000173193
4  ENSG00000138496 NA PARP9 poly (ADP-ribose) polymerase family, member 9 83666 ENSG00000138496


Database:molecular function       Name:transferase activity, transferring pentosyl groups       ID:GO:0016763
C=50; O=5; E=0.35; R=14.15; rawP=2.64e-05; adjP=0.0009
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000025708 NA TYMP thymidine phosphorylase 1890 ENSG00000025708
2  ENSG00000059378 NA PARP12 poly (ADP-ribose) polymerase family, member 12 64761 ENSG00000059378
3  ENSG00000178685 NA PARP10 poly (ADP-ribose) polymerase family, member 10 84875 ENSG00000178685
4  ENSG00000173193 NA PARP14 poly (ADP-ribose) polymerase family, member 14 54625 ENSG00000173193
5  ENSG00000138496 NA PARP9 poly (ADP-ribose) polymerase family, member 9 83666 ENSG00000138496


Database:molecular function       Name:pyrophosphatase activity       ID:GO:0016462
C=794; O=16; E=5.61; R=2.85; rawP=0.0001; adjP=0.0017
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000107201 NA DDX58 DEAD (Asp-Glu-Ala-Asp) box polypeptide 58 23586 ENSG00000107201
2  ENSG00000157601 NA MX1 myxovirus (influenza virus) resistance 1, interferon-inducible protein p78 (mouse) 4599 ENSG00000157601
3  ENSG00000117226 NA GBP3 guanylate binding protein 3 2635 ENSG00000117226
4  ENSG00000173821 NA RNF213 ring finger protein 213 57674 ENSG00000173821
5  ENSG00000168394 NA TAP1 transporter 1, ATP-binding cassette, sub-family B (MDR/TAP) 6890 ENSG00000168394
6  ENSG00000143761 NA ARF1 ADP-ribosylation factor 1 375 ENSG00000143761
7  ENSG00000162654 NA GBP4 guanylate binding protein 4 115361 ENSG00000162654
8  ENSG00000183486 NA MX2 myxovirus (influenza virus) resistance 2 (mouse) 4600 ENSG00000183486
9  ENSG00000181381 NA DDX60L DEAD (Asp-Glu-Ala-Asp) box polypeptide 60-like 91351 ENSG00000181381
10  ENSG00000130589 NA PRIC285 peroxisomal proliferator-activated receptor A interacting complex 285 85441 ENSG00000130589
11  ENSG00000108771 NA DHX58 DEXH (Asp-Glu-X-His) box polypeptide 58 79132 ENSG00000108771
12  ENSG00000117228 NA GBP1 guanylate binding protein 1, interferon-inducible 2633 ENSG00000117228
13  ENSG00000162645 NA GBP2 guanylate binding protein 2, interferon-inducible 2634 ENSG00000162645
14  ENSG00000204267 NA TAP2 transporter 2, ATP-binding cassette, sub-family B (MDR/TAP) 6891 ENSG00000204267 ENSG00000250264
15  ENSG00000155363 NA MOV10 Mov10, Moloney leukemia virus 10, homolog (mouse) 4343 ENSG00000155363
16  ENSG00000115267 NA IFIH1 interferon induced with helicase C domain 1 64135 ENSG00000115267


Database:molecular function       Name:hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides       ID:GO:0016818
C=797; O=16; E=5.63; R=2.84; rawP=0.0001; adjP=0.0017
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000107201 NA DDX58 DEAD (Asp-Glu-Ala-Asp) box polypeptide 58 23586 ENSG00000107201
2  ENSG00000157601 NA MX1 myxovirus (influenza virus) resistance 1, interferon-inducible protein p78 (mouse) 4599 ENSG00000157601
3  ENSG00000117226 NA GBP3 guanylate binding protein 3 2635 ENSG00000117226
4  ENSG00000173821 NA RNF213 ring finger protein 213 57674 ENSG00000173821
5  ENSG00000168394 NA TAP1 transporter 1, ATP-binding cassette, sub-family B (MDR/TAP) 6890 ENSG00000168394
6  ENSG00000143761 NA ARF1 ADP-ribosylation factor 1 375 ENSG00000143761
7  ENSG00000162654 NA GBP4 guanylate binding protein 4 115361 ENSG00000162654
8  ENSG00000183486 NA MX2 myxovirus (influenza virus) resistance 2 (mouse) 4600 ENSG00000183486
9  ENSG00000181381 NA DDX60L DEAD (Asp-Glu-Ala-Asp) box polypeptide 60-like 91351 ENSG00000181381
10  ENSG00000130589 NA PRIC285 peroxisomal proliferator-activated receptor A interacting complex 285 85441 ENSG00000130589
11  ENSG00000108771 NA DHX58 DEXH (Asp-Glu-X-His) box polypeptide 58 79132 ENSG00000108771
12  ENSG00000117228 NA GBP1 guanylate binding protein 1, interferon-inducible 2633 ENSG00000117228
13  ENSG00000162645 NA GBP2 guanylate binding protein 2, interferon-inducible 2634 ENSG00000162645
14  ENSG00000204267 NA TAP2 transporter 2, ATP-binding cassette, sub-family B (MDR/TAP) 6891 ENSG00000204267 ENSG00000250264
15  ENSG00000155363 NA MOV10 Mov10, Moloney leukemia virus 10, homolog (mouse) 4343 ENSG00000155363
16  ENSG00000115267 NA IFIH1 interferon induced with helicase C domain 1 64135 ENSG00000115267


Database:molecular function       Name:nucleoside-triphosphatase activity       ID:GO:0017111
C=760; O=16; E=5.37; R=2.98; rawP=8.36e-05; adjP=0.0017
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000107201 NA DDX58 DEAD (Asp-Glu-Ala-Asp) box polypeptide 58 23586 ENSG00000107201
2  ENSG00000157601 NA MX1 myxovirus (influenza virus) resistance 1, interferon-inducible protein p78 (mouse) 4599 ENSG00000157601
3  ENSG00000117226 NA GBP3 guanylate binding protein 3 2635 ENSG00000117226
4  ENSG00000173821 NA RNF213 ring finger protein 213 57674 ENSG00000173821
5  ENSG00000168394 NA TAP1 transporter 1, ATP-binding cassette, sub-family B (MDR/TAP) 6890 ENSG00000168394
6  ENSG00000143761 NA ARF1 ADP-ribosylation factor 1 375 ENSG00000143761
7  ENSG00000162654 NA GBP4 guanylate binding protein 4 115361 ENSG00000162654
8  ENSG00000183486 NA MX2 myxovirus (influenza virus) resistance 2 (mouse) 4600 ENSG00000183486
9  ENSG00000181381 NA DDX60L DEAD (Asp-Glu-Ala-Asp) box polypeptide 60-like 91351 ENSG00000181381
10  ENSG00000130589 NA PRIC285 peroxisomal proliferator-activated receptor A interacting complex 285 85441 ENSG00000130589
11  ENSG00000108771 NA DHX58 DEXH (Asp-Glu-X-His) box polypeptide 58 79132 ENSG00000108771
12  ENSG00000117228 NA GBP1 guanylate binding protein 1, interferon-inducible 2633 ENSG00000117228
13  ENSG00000162645 NA GBP2 guanylate binding protein 2, interferon-inducible 2634 ENSG00000162645
14  ENSG00000204267 NA TAP2 transporter 2, ATP-binding cassette, sub-family B (MDR/TAP) 6891 ENSG00000204267 ENSG00000250264
15  ENSG00000155363 NA MOV10 Mov10, Moloney leukemia virus 10, homolog (mouse) 4343 ENSG00000155363
16  ENSG00000115267 NA IFIH1 interferon induced with helicase C domain 1 64135 ENSG00000115267


Database:molecular function       Name:tapasin binding       ID:GO:0046980
C=3; O=2; E=0.02; R=94.35; rawP=0.0001; adjP=0.0017
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000204267 NA TAP2 transporter 2, ATP-binding cassette, sub-family B (MDR/TAP) 6891 ENSG00000204267 ENSG00000250264
2  ENSG00000168394 NA TAP1 transporter 1, ATP-binding cassette, sub-family B (MDR/TAP) 6890 ENSG00000168394


Database:cellular component       Name:MHC protein complex       ID:GO:0042611
C=38; O=12; E=0.28; R=43.43; rawP=2.93e-17; adjP=3.78e-15
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000196126 NA HLA-DRB1 major histocompatibility complex, class II, DR beta 1 3123 ENSG00000196126
2  ENSG00000204287 NA HLA-DRA major histocompatibility complex, class II, DR alpha 3122 ENSG00000204287
3  ENSG00000204257 NA HLA-DMA major histocompatibility complex, class II, DM alpha 3108 ENSG00000204257
4  ENSG00000231389 NA HLA-DPA1 major histocompatibility complex, class II, DP alpha 1 3113 ENSG00000231389
5  ENSG00000196735 NA HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1 3117 ENSG00000196735
6  ENSG00000204592 NA HLA-E major histocompatibility complex, class I, E 3133 ENSG00000204592
7  ENSG00000204642 NA HLA-F major histocompatibility complex, class I, F 3134 ENSG00000204642
8  ENSG00000242574 NA HLA-DMB major histocompatibility complex, class II, DM beta 3109 ENSG00000242574
9  ENSG00000166710 NA B2M beta-2-microglobulin 567 ENSG00000166710
10  ENSG00000204252 NA HLA-DOA major histocompatibility complex, class II, DO alpha 3111 ENSG00000204252
11  ENSG00000223865 NA HLA-DPB1 major histocompatibility complex, class II, DP beta 1 3115 ENSG00000223865
12  ENSG00000019582 NA CD74 CD74 molecule, major histocompatibility complex, class II invariant chain 972 ENSG00000019582


Database:cellular component       Name:MHC class II protein complex       ID:GO:0042613
C=16; O=9; E=0.12; R=77.36; rawP=4.64e-16; adjP=2.99e-14
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000196126 NA HLA-DRB1 major histocompatibility complex, class II, DR beta 1 3123 ENSG00000196126
2  ENSG00000204287 NA HLA-DRA major histocompatibility complex, class II, DR alpha 3122 ENSG00000204287
3  ENSG00000204257 NA HLA-DMA major histocompatibility complex, class II, DM alpha 3108 ENSG00000204257
4  ENSG00000231389 NA HLA-DPA1 major histocompatibility complex, class II, DP alpha 1 3113 ENSG00000231389
5  ENSG00000204252 NA HLA-DOA major histocompatibility complex, class II, DO alpha 3111 ENSG00000204252
6  ENSG00000196735 NA HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1 3117 ENSG00000196735
7  ENSG00000223865 NA HLA-DPB1 major histocompatibility complex, class II, DP beta 1 3115 ENSG00000223865
8  ENSG00000019582 NA CD74 CD74 molecule, major histocompatibility complex, class II invariant chain 972 ENSG00000019582
9  ENSG00000242574 NA HLA-DMB major histocompatibility complex, class II, DM beta 3109 ENSG00000242574


Database:cellular component       Name:ER to Golgi transport vesicle membrane       ID:GO:0012507
C=37; O=9; E=0.27; R=33.45; rawP=4.44e-12; adjP=1.91e-10
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000196126 NA HLA-DRB1 major histocompatibility complex, class II, DR beta 1 3123 ENSG00000196126
2  ENSG00000204287 NA HLA-DRA major histocompatibility complex, class II, DR alpha 3122 ENSG00000204287
3  ENSG00000231389 NA HLA-DPA1 major histocompatibility complex, class II, DP alpha 1 3113 ENSG00000231389
4  ENSG00000166710 NA B2M beta-2-microglobulin 567 ENSG00000166710
5  ENSG00000196735 NA HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1 3117 ENSG00000196735
6  ENSG00000223865 NA HLA-DPB1 major histocompatibility complex, class II, DP beta 1 3115 ENSG00000223865
7  ENSG00000204592 NA HLA-E major histocompatibility complex, class I, E 3133 ENSG00000204592
8  ENSG00000204642 NA HLA-F major histocompatibility complex, class I, F 3134 ENSG00000204642
9  ENSG00000019582 NA CD74 CD74 molecule, major histocompatibility complex, class II invariant chain 972 ENSG00000019582


Database:cellular component       Name:ER to Golgi transport vesicle       ID:GO:0030134
C=41; O=9; E=0.30; R=30.19; rawP=1.22e-11; adjP=3.93e-10
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000196126 NA HLA-DRB1 major histocompatibility complex, class II, DR beta 1 3123 ENSG00000196126
2  ENSG00000204287 NA HLA-DRA major histocompatibility complex, class II, DR alpha 3122 ENSG00000204287
3  ENSG00000231389 NA HLA-DPA1 major histocompatibility complex, class II, DP alpha 1 3113 ENSG00000231389
4  ENSG00000166710 NA B2M beta-2-microglobulin 567 ENSG00000166710
5  ENSG00000196735 NA HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1 3117 ENSG00000196735
6  ENSG00000223865 NA HLA-DPB1 major histocompatibility complex, class II, DP beta 1 3115 ENSG00000223865
7  ENSG00000204592 NA HLA-E major histocompatibility complex, class I, E 3133 ENSG00000204592
8  ENSG00000204642 NA HLA-F major histocompatibility complex, class I, F 3134 ENSG00000204642
9  ENSG00000019582 NA CD74 CD74 molecule, major histocompatibility complex, class II invariant chain 972 ENSG00000019582


Database:cellular component       Name:integral to lumenal side of endoplasmic reticulum membrane       ID:GO:0071556
C=28; O=8; E=0.20; R=39.29; rawP=1.71e-11; adjP=4.41e-10
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000196126 NA HLA-DRB1 major histocompatibility complex, class II, DR beta 1 3123 ENSG00000196126
2  ENSG00000204287 NA HLA-DRA major histocompatibility complex, class II, DR alpha 3122 ENSG00000204287
3  ENSG00000231389 NA HLA-DPA1 major histocompatibility complex, class II, DP alpha 1 3113 ENSG00000231389
4  ENSG00000196735 NA HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1 3117 ENSG00000196735
5  ENSG00000223865 NA HLA-DPB1 major histocompatibility complex, class II, DP beta 1 3115 ENSG00000223865
6  ENSG00000204592 NA HLA-E major histocompatibility complex, class I, E 3133 ENSG00000204592
7  ENSG00000204642 NA HLA-F major histocompatibility complex, class I, F 3134 ENSG00000204642
8  ENSG00000019582 NA CD74 CD74 molecule, major histocompatibility complex, class II invariant chain 972 ENSG00000019582


Database:cellular component       Name:lysosomal membrane       ID:GO:0005765
C=140; O=12; E=1.02; R=11.79; rawP=4.23e-10; adjP=9.09e-09
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000196126 NA HLA-DRB1 major histocompatibility complex, class II, DR beta 1 3123 ENSG00000196126
2  ENSG00000204287 NA HLA-DRA major histocompatibility complex, class II, DR alpha 3122 ENSG00000204287
3  ENSG00000204257 NA HLA-DMA major histocompatibility complex, class II, DM alpha 3108 ENSG00000204257
4  ENSG00000231389 NA HLA-DPA1 major histocompatibility complex, class II, DP alpha 1 3113 ENSG00000231389
5  ENSG00000164342 NA TLR3 toll-like receptor 3 7098 ENSG00000164342
6  ENSG00000110446 NA SLC15A3 solute carrier family 15, member 3 51296 ENSG00000110446
7  ENSG00000196735 NA HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1 3117 ENSG00000196735
8  ENSG00000242574 NA HLA-DMB major histocompatibility complex, class II, DM beta 3109 ENSG00000242574
9  ENSG00000204252 NA HLA-DOA major histocompatibility complex, class II, DO alpha 3111 ENSG00000204252
10  ENSG00000223865 NA HLA-DPB1 major histocompatibility complex, class II, DP beta 1 3115 ENSG00000223865
11  ENSG00000138463 NA DIRC2 disrupted in renal carcinoma 2 84925 ENSG00000138463
12  ENSG00000019582 NA CD74 CD74 molecule, major histocompatibility complex, class II invariant chain 972 ENSG00000019582


Database:cellular component       Name:transport vesicle membrane       ID:GO:0030658
C=76; O=9; E=0.55; R=16.29; rawP=4.01e-09; adjP=7.39e-08
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000196126 NA HLA-DRB1 major histocompatibility complex, class II, DR beta 1 3123 ENSG00000196126
2  ENSG00000204287 NA HLA-DRA major histocompatibility complex, class II, DR alpha 3122 ENSG00000204287
3  ENSG00000231389 NA HLA-DPA1 major histocompatibility complex, class II, DP alpha 1 3113 ENSG00000231389
4  ENSG00000166710 NA B2M beta-2-microglobulin 567 ENSG00000166710
5  ENSG00000196735 NA HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1 3117 ENSG00000196735
6  ENSG00000223865 NA HLA-DPB1 major histocompatibility complex, class II, DP beta 1 3115 ENSG00000223865
7  ENSG00000204592 NA HLA-E major histocompatibility complex, class I, E 3133 ENSG00000204592
8  ENSG00000204642 NA HLA-F major histocompatibility complex, class I, F 3134 ENSG00000204642
9  ENSG00000019582 NA CD74 CD74 molecule, major histocompatibility complex, class II invariant chain 972 ENSG00000019582


Database:cellular component       Name:integral to endoplasmic reticulum membrane       ID:GO:0030176
C=106; O=10; E=0.77; R=12.97; rawP=5.06e-09; adjP=8.16e-08
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000196126 NA HLA-DRB1 major histocompatibility complex, class II, DR beta 1 3123 ENSG00000196126
2  ENSG00000204287 NA HLA-DRA major histocompatibility complex, class II, DR alpha 3122 ENSG00000204287
3  ENSG00000231389 NA HLA-DPA1 major histocompatibility complex, class II, DP alpha 1 3113 ENSG00000231389
4  ENSG00000196735 NA HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1 3117 ENSG00000196735
5  ENSG00000204592 NA HLA-E major histocompatibility complex, class I, E 3133 ENSG00000204592
6  ENSG00000204642 NA HLA-F major histocompatibility complex, class I, F 3134 ENSG00000204642
7  ENSG00000168394 NA TAP1 transporter 1, ATP-binding cassette, sub-family B (MDR/TAP) 6890 ENSG00000168394
8  ENSG00000204267 NA TAP2 transporter 2, ATP-binding cassette, sub-family B (MDR/TAP) 6891 ENSG00000204267 ENSG00000250264
9  ENSG00000223865 NA HLA-DPB1 major histocompatibility complex, class II, DP beta 1 3115 ENSG00000223865
10  ENSG00000019582 NA CD74 CD74 molecule, major histocompatibility complex, class II invariant chain 972 ENSG00000019582


Database:cellular component       Name:vacuolar membrane       ID:GO:0005774
C=184; O=12; E=1.34; R=8.97; rawP=9.67e-09; adjP=1.39e-07
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000196126 NA HLA-DRB1 major histocompatibility complex, class II, DR beta 1 3123 ENSG00000196126
2  ENSG00000204287 NA HLA-DRA major histocompatibility complex, class II, DR alpha 3122 ENSG00000204287
3  ENSG00000204257 NA HLA-DMA major histocompatibility complex, class II, DM alpha 3108 ENSG00000204257
4  ENSG00000231389 NA HLA-DPA1 major histocompatibility complex, class II, DP alpha 1 3113 ENSG00000231389
5  ENSG00000164342 NA TLR3 toll-like receptor 3 7098 ENSG00000164342
6  ENSG00000110446 NA SLC15A3 solute carrier family 15, member 3 51296 ENSG00000110446
7  ENSG00000196735 NA HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1 3117 ENSG00000196735
8  ENSG00000242574 NA HLA-DMB major histocompatibility complex, class II, DM beta 3109 ENSG00000242574
9  ENSG00000204252 NA HLA-DOA major histocompatibility complex, class II, DO alpha 3111 ENSG00000204252
10  ENSG00000223865 NA HLA-DPB1 major histocompatibility complex, class II, DP beta 1 3115 ENSG00000223865
11  ENSG00000138463 NA DIRC2 disrupted in renal carcinoma 2 84925 ENSG00000138463
12  ENSG00000019582 NA CD74 CD74 molecule, major histocompatibility complex, class II invariant chain 972 ENSG00000019582


Database:cellular component       Name:intrinsic to endoplasmic reticulum membrane       ID:GO:0031227
C=123; O=10; E=0.89; R=11.18; rawP=2.15e-08; adjP=2.77e-07
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000196126 NA HLA-DRB1 major histocompatibility complex, class II, DR beta 1 3123 ENSG00000196126
2  ENSG00000204287 NA HLA-DRA major histocompatibility complex, class II, DR alpha 3122 ENSG00000204287
3  ENSG00000231389 NA HLA-DPA1 major histocompatibility complex, class II, DP alpha 1 3113 ENSG00000231389
4  ENSG00000196735 NA HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1 3117 ENSG00000196735
5  ENSG00000204592 NA HLA-E major histocompatibility complex, class I, E 3133 ENSG00000204592
6  ENSG00000204642 NA HLA-F major histocompatibility complex, class I, F 3134 ENSG00000204642
7  ENSG00000168394 NA TAP1 transporter 1, ATP-binding cassette, sub-family B (MDR/TAP) 6890 ENSG00000168394
8  ENSG00000204267 NA TAP2 transporter 2, ATP-binding cassette, sub-family B (MDR/TAP) 6891 ENSG00000204267 ENSG00000250264
9  ENSG00000223865 NA HLA-DPB1 major histocompatibility complex, class II, DP beta 1 3115 ENSG00000223865
10  ENSG00000019582 NA CD74 CD74 molecule, major histocompatibility complex, class II invariant chain 972 ENSG00000019582




WebGestalt is currently developed and maintained by Jing Wang and Bing Zhang at the Zhang Lab. Other people who have made significant contribution to the project include Dexter Duncan, Stefan Kirov, Zhiao Shi, and Jay Snoddy.

Funding credits: NIH/NIAAA (U01 AA016662, U01 AA013512); NIH/NIDA (P01 DA015027); NIH/NIMH (P50 MH078028, P50 MH096972); NIH/NCI (U24 CA159988); NIH/NIGMS (R01 GM088822).